Small-blue-round-cell tumor

src: www.tumorsurgery.org

In histopathology, a small-blue-round-cell tumour (abbreviated SBRCT), also known as a small-round-blue-cell tumor (SRBCT) or a small-round-cell tumour (SRCT), is any one of a group of malignant neoplasms that have a characteristic appearance under the microscope, i.e. consisting of small round cells that stain blue on routine H&E stained sections.

These tumors are seen more often in children than in adults. They typically represent undifferentiated cells. The predominance of blue staining is because the cells consist predominantly of nucleus, thus they have scant cytoplasm.

Video Small-blue-round-cell tumor

Examples

Tumors that belong to this group are:

• Desmoplastic small-round-cell tumour
• Ewing's Sarcoma/PNET
• Neuroblastoma
• Medulloblastoma
• Rhabdomyosarcoma
• Synovial sarcoma
• Carcinoid tumor
• Mesothelioma
• Small cell lung cancer
• Wilms' tumour
• Retinoblastoma
• Small-cell lymphoma
• Hepatoblastoma- only the anaplastic form has round blue cells, the more common fetal and embryonal types do not
• Merkel cell carcinoma
• Mesenchymal chondrosarcoma

Maps Small-blue-round-cell tumor

Conditions mimicking SBRCT

Endometrial stromal condensation may mimic a small-blue-round-cell tumour.

src: www.humpath.com

References

Source of the article : Wikipedia