Frederic Edward Mohs (March 1, 1910 - July 2, 2002), a physician and general surgeon, developed Mohs micrographic surgery (MMS) technique in 1938 to remove skin cancer lesions while still a medical student at the University Wisconsin-Madison. The Mohs procedure is considered the best method for treating certain types of skin cancer, as it has a very high cure rate even for high-risk lesions, combined with maximum healthy tissue preservation.
Video Frederic E. Mohs
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Mohs was born in Burlington, Wisconsin. His father died when he was 3 months old, and his family moved to Madison, where his mother ran a boarding house. After initially considering a career as a radio engineer, he turned to medical studies at college.
Maps Frederic E. Mohs
Medical career
Mohs began to develop his treatment in the 1930s, experimenting on mice, puppies, and other animals. The breakthrough came when he discovered that the use of a combination of zinc chloride and bloodroot paste into a malignant rat skin tissue enabled him to be removed surgically and examined under a microscope. He took care of his first human patient on June 23, 1936. Mohs spent his time at the University of Wisconsin.
Mohs first tried to publish his findings and encouraged the surgeon to learn the procedure. This is largely unsuccessful, as many surgeons are uncomfortable studying skin pathology and laboratory techniques. Dermatologists, trained in dermatopathology, and who treat skin cancer every day, quickly apply this procedure. Currently, most of the Mohs procedures are performed by dermatologists, although a small number of plastic surgeons, otolaryngologists, and pathologists also practice and use this procedure as well.
The Mohs technique was later modified by Perry Robins in the 1970s, using frozen histology of fresh tissue. Instead of using Mohs anesthesia paste, local anesthesia is used. Fresh skin specimen is then mounted on the cryostat, and the frozen section is checked in place of the fixed portion of the Mohs pasta. This method is now often referred to as the Mohs operation, and sometimes chemosurgery refers to the Mohs paste originally used by Mohs.
Personal life
In 1943, Mohs married Mary Ellen Reynolds, who died in 1995. Mohs died at his home in Madison, Wisconsin on July 2, 2002 at the age of 92. He survived by two sons, Frederic and Thomas, from Madison; and a daughter, Jane Schimming from Stuart, Fla.
References
Source of the article : Wikipedia